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Central Nervous System
Helping you make a dramatic impact on quality of life for people with neurological disorders.
Home / Therapeutic Areas / CNS
Helping you make a dramatic impact on quality of life for people with neurological disorders.
At Sigma-Chi, we share your deep commitment to developing therapies to alleviate these conditions. Yet the challenges of CNS diseases bring associated challenges to conducting clinical trials. Cognitive impairment, memory loss, reduced movement and sensory capabilities – these create a high burden of disease on patients as well as the caregivers on whom many are dependent.
Trial endpoints can be inadvertently influenced by patient expectations, placebo effects, and investigator biases. Highly specialized expertise, scrupulous quality control, and a patient-centric approach are paramount.
For more than 7 years, Sigma-Chi has been at the forefront of CNS clinical development projects worldwide, involving some 150 trials and more than 20 indications. Our expertise includes movement, demyelinating, and seizure disorders, as well as neurodegenerative and neurovascular diseases. We interact extensively with regulatory agencies in the U.S. and Europe to keep pace with the stipulations and advances in CNS trials and treatments.
We share your commitment to developing therapies for CNS conditions. These diseases also bring challenges for clinical trials: cognitive impairment, memory loss and reduced movement and sensory capabilities place a high burden on patients and their caregivers.
Trial endpoints can be influenced by patient expectations, placebo effects and investigator bias, so specialised expertise, scrupulous quality control and a patient-centric approach are essential.
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